Anti-Human CD27 PE
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes.
CD27 is a marker of memory B cells.
Mouse IgG1, kappa
|Research Interest:||Adaptive Immunity, Apoptosis|
|Cell Type:||B Cells, T Cells, NK and NKT Cells|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., & Silva-Santos, B. (2011). Differentiation of human peripheral blood Vδ1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells. Blood, 118(4), 992-1001.