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Anti-Human CD21 APC



Catalog Number : 03311-80

Description

The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein. CD21 is reported to be involved in B cell activation and proliferation. It is expressed on follicular dendritic cells, mature B cells, a subset of T cells, and a subset of epithelial cells. It is the receptor utilized by the Epstein-Barr virus to infect B cells.

Additional Information

Clone:
HB5
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Tedder, T. F., Clement, L. T., & Cooper, M. D. (1984). Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody. The Journal of Immunology133(2), 678-683.

Fingeroth, J. D., Weis, J. J., Tedder, T. F., Strominger, J. L., Biro, P. A., & Fearon, D. T. (1984). Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proceedings of the National Academy of Sciences,81(14), 4510-4514.

Nemerow, G. R., Wolfert, R. O. B. E. R. T., McNaughton, M. E., & Cooper, N. R. (1985). Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2). Journal of virology55(2), 347-351.


Availability: In stock

Size Price Qty
25 tests
$155.00
100 tests
$320.00
Additional HB5 Formats
Cat.No. Format Starting From
03311-50FITC $ 100.00
03311-60PE $ 110.00
03311-80APC $ 155.00