Anti-Human CD20 BG Violet 450

Grouped product items
Size Price Qty
25 tests
$125.00
100 tests
$270.00

Additional 2H7 Formats

Cat.No. Format Starting From
02311-80 APC $ 455.00
02311-20 Purified $ 170.00
02311-60 PE $ 100.00
02311-40 BG Violet 450 $ 125.00
02311-50 FITC $ 70.00
02311-87 APC-Cyanine7 $ 145.00
02311-70 PerCP-Cyanine5.5 $ 170.00
02311-77 PE-Cyanine7 $ 150.00
02311-30 Biotin $ 85.00
Catalog Number : 02311-40

description

The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.

Additional Information

Clone:
2H7
Format:
BG Violet 450
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2b, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells
Application: FC
Clone: 2H7
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Polyak, M. J., & Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure. Blood99(9), 3256-3262.

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

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