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Anti-Human CD2 SAFIRE Purified



Catalog Number : 04111-25

Description

The RPA-2.10 monoclonal antibody specifically binds to human CD2, a 50 kDA type I transmembrane glycoprotein. CD2 is expressed on NK cells, thymocytes, T lymphocytes, and B cell subsets. CD2 is involved in cell-cell adhesion, T cell activation, and T cell signaling. Its ligand is CD58 and it is reported to bind to CD48, CD59, and CD15. The RPA-2.10 antibody is reported to be cross-reactive with pigs and non-human primates..

Additional Information

Clone:
RPA-2.10
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells, T Cells, NK and NKT Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Hahn, W. C., Burakoff, S. J., & Bierer, B. E. (1993). Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.The Journal of Immunology150(7), 2607-2619.

Aversa, G. G., Bishop, G. A., Suranyi, M. G., & Hall, B. M. (1987, February). RPA-2.10: an anti-CD2 monoclonal antibody that inhibits alloimmune responses and monitors T cell activation. In Transplantation proceedings (Vol. 19, No. 1 Pt 1, pp. 277-278).


Availability: In stock

Size Price Qty
50 ug
$130.00
500 ug
$360.00
Additional RPA-2.10 Formats
Cat.No. Format Starting From
04111-25SAFIRE Purified $ 130.00
04111-80APC $ 105.00
04111-60PE $ 90.00
04111-50FITC $ 75.00
04111-40BG Violet 450 $ 110.00