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Anti-Human CD193 (CCR3) PE



Catalog Number : 16011-60

Description

The 5E8-G9-B4 monoclonal antibody specifically reacts with human CD193, also known as CKR3 and CCR3. CD193. CD193 is a G protein-coupled seven transmembrane receptor that binds to eotaxin-1,2,3 and to a lesser degree to MCP-3,4 and RANTES. It is expressed on eosinophils and basophils, mast cells platelets, CD34+ hematopoietic progenitor, and mononuclear phagocytes. CD193 plays a role in asthma and is a co-receptor for HIV-1,2.

Additional Information

Clone:
5E8-G9-B4
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2b, kappa
Research Interest: Stem Cell Research, Cytokines & Growth Factors, Angiogenesis
Cell Type: T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Agrawal, L., Maxwell, C. R., Peters, P. J., Clapham, P. R., Liu, S. M., Mackay, C. R., & Strayer, D. S. (2009). Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia. Journal of General Virology90(3), 710-722.

Heath, H., Qin, S., Rao, P., Wu, L., LaRosa, G., Kassam, N., ... & Mackay, C. R. (1997). Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. Journal of Clinical Investigation99(2), 178.

Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., ... & Sodroski, J. (1996). The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell85(7), 1135-1148.


Availability: In stock

Size Price Qty
25 tests
$90.00
100 tests
$180.00
Additional 5E8-G9-B4 Formats
Cat.No. Format Starting From
16011-60PE $ 90.00