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Anti-Human CD14 SAFIRE Purified



Catalog Number : 06211-25

Description

The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS). It is expressed on some dendritic cells, monocytes, and neutrophils. CD14 is involved in the body’s innate immune response and cytokine expression in monocytes and neutrophils.

Additional Information

Clone:
61D3
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity
Cell Type: Monocytes and Macrophages
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Nunez, G., Ugolini, V., Capra, J. D., & Stastny, P. (1982). Monoclonal Antibodies against Human Monocytes. Scandinavian journal of immunology,16(6), 515-523

Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature392(6675), 505-509.

Henriksen, P. A., Devitt, A., Kotelevtsev, Y., & Sallenave, J. M. (2004). Gene delivery of the elastase inhibitor elafin protects macrophages from neutrophil elastase-mediated impairment of apoptotic cell recognition. FEBS letters,574(1), 80-84.


Availability: In stock

Size Price Qty
100 ug
$275.00
Additional 61D3 Formats
Cat.No. Format Starting From
06211-50FITC $ 80.00
06211-70PerCP-Cyanine5.5 $ 190.00
06211-80APC $ 120.00
06211-25SAFIRE Purified $ 275.00
06211-40BG Violet 450 $ 100.00
06211-60PE $ 100.00