Anti-Human CD14 PerCP-Cy 5.5
Additional 61D3 Formats
Cat.No. | Format | Starting From |
---|---|---|
06211-50 | FITC | $ 80.00 |
06211-70 | PerCP-Cyanine5.5 | $ 305.00 |
06211-80 | APC | $ 120.00 |
06211-25 | SAFIRE Purified | $ 440.00 |
06211-40 | BG Violet 450 | $ 100.00 |
06211-60 | PE | $ 100.00 |
Catalog Number : 06211-70
description
The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Additional Information
Clone:
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61D3
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Format:
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PerCP-Cyanine5.5
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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Research Interest: | Innate Immunity |
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Cell Type: | Macrophage / Monocyte |
Application: | FC |
Clone: | 61D3 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998. Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature, 392(6675), 505-509. |