Anti-Human CD14 PerCP-Cy 5.5

Catalog Number : 06211-70

Description

The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.

Additional Information

Clone:	61D3
Format:	PerCP-Cyanine5.5
Applications:	FC
Reactivity:	Human
Isotype:	Mouse IgG1, kappa
Research Interest:	Innate Immunity
Cell Type:	Monocytes and Macrophages
Preparation:	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:	Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998. Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature, 392(6675), 505-509.

Availability: In stock

Size	Price	Qty
25 tests	$190.00
100 tests	$370.00

Additional 61D3 Formats

Cat.No.	Format	Starting From
06211-50	FITC	$ 80.00
06211-70	PerCP-Cyanine5.5	$ 190.00
06211-80	APC	$ 120.00
06211-25	SAFIRE Purified	$ 275.00
06211-40	BG Violet 450	$ 100.00
06211-60	PE	$ 100.00