Anti-Human CD137L (4-1BB Ligand) APC
Catalog Number : 19461-80
description
The 4H3 monoclonal antibody bind to human CD137 Ligand or 4-1BBL, a type II membrane protein in the TNF superfamily. It is mainly expressed on antigen presenting cells, and activated B and T cells. Ligation of 4-1BB on T cells and natural killer cells induces cell activation, promotes survival, and enhances effector functions.
Additional Information
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Clone:
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4H3
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | B Cells, Macrophage / Monocyte, T Cells |
| Application: | FC |
| Clone: | 4H3 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Jung, H. W., Choi, S. W., Choi, J. I., & Kwon, B. S. (2004). Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis. Experimental & molecular medicine, 36(1), 13. |