Anti-Human CD137 (4-1BB) PE-Cyanine7
Additional 4B4 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 19411-77 | PE-Cyanine7 | $ 600.00 |
Catalog Number : 19411-77
description
The 4B4 monoclonal antibody reacts with human CD137 (4-1BB), a type I membrane protein and member of the TNFR family. It is expressed on NK cells, T cells, dendritic cells, and mast cells and plays a role in T cell activation and proliferation.
Additional Information
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Clone:
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4B4
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Format:
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PE-Cyanine7
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells, NK and NKT Cells |
| Application: | FC |
| Clone: | 4B4 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Kienzle, G., & von Kempis, J. (2000). CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes. International immunology, 12(1), 73-82. Lin, W., Voskens, C. J., Zhang, X., Schindler, D. G., Wood, A., Burch, E., ... & Wang, L. X. (2008). Fc-dependent expression of CD137 on human NK cells: insights into “agonistic” effects of anti-CD137 monoclonal antibodies. Blood, 112(3), 699-707. Kim, K. M., Kim, H. W., Kim, J. O., Baek, K. M., Kim, J. G., & Kang, C. Y. (2002). Induction of 4‐1BB (CD137) expression by DNA damaging agents in human T lymphocytes. Immunology, 107(4), 472-479. |