Anti-Human CD123 APC

Grouped product items
Size Price Qty
100 tests
$515.00

Additional 6H6 Formats

Cat.No. Format Starting From
15311-60 PE $ 155.00
15311-80 APC $ 515.00
15311-20 Purified $ 190.00
Catalog Number : 15311-80

description

The 6H6 monoclonal antibody specifically reacts with human CD123, the alpha chain subunit of the IL-3 receptor. CD123’s affinity to IL-3 is low, but increases when associated with CD131. It can be found on basophils, dendritic cells, macrophages, and mast cells.

Additional Information

Clone:
6H6
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Stem Cell Research, Cytokines & Growth Factors
Cell Type: B Cells, Dendritic Cells
Application: FC
Clone: 6H6
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Herling, M., Teitell, M. A., Shen, R. R., Medeiros, L. J., & Jones, D. (2003). TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood101(12), 5007-5009.

Peduzzi, E., Groeper, C., Schütte, D., Zajac, P., Rondini, S., Mensah-Quainoo, E., ... & Daubenberger, C. A. (2007). Local activation of the innate immune system in Buruli ulcer lesions. Journal of Investigative Dermatology127(3), 638-645.

Sun, Q., Woodcock, J. M., Rapoport, A., Stomski, F. C., Korpelainen, E. I., Bagley, C. J., ... & Lopez, A. F. (1996). Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. Blood87(1), 83-92.

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