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Anti-Human CD11a SAFIRE Purified



Catalog Number : 03241-25

Description

The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2).

Additional Information

Clone:
HI111
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Angiogenesis
Cell Type: Treg cells, Th1 cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Inghirami, G., Wieczorek, R., Zhu, B. Y., Silber, R., Dalla-Favera, R., & Knowles, D. M. (1988). Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia. Blood72(4), 1431-1434.

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse-Anthony, C. P., ... & Schleimer, R. P. (1991). Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. The Journal of experimental medicine173(6), 1553-1557.


Availability: In stock

Size Price Qty
50 ug
$120.00
500 ug
$360.00
Additional HI111 Formats
Cat.No. Format Starting From
03241-25SAFIRE Purified $ 120.00