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Anti-Human CD106 (VCAM-1) PE



Catalog Number : 18111-60

Description

The STA monoclonal antibody specifically reacts with human CD106, a 110 kDA glycoprotein also named Vascular Cell Adhesion Molecule-1 (VCAM-1) and INCAM-110. Its expression is induced by inflammation stimuli and cytokines and it is found mainly on activated vascular endothelium. CD106 is also found on subsets of macrophages, stromal cells, dendritic cells, and myeloid lineage cells. The integrins that bind CD106 are CD49d/CD29 and LPAM-1, and it is involved in cell adhesion, transmigration and T cell proliferation.

Additional Information

Clone:
STA
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity, Angiogenesis
Cell Type: B Cells, Monocytes and Macrophages, T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Wagner, B. J., Lindau, D., Ripper, D., Stierhof, Y. D., Glatzle, J., Witte, M., ... & Königsrainer, A. (2011). Phagocytosis of dying tumor cells by human peritoneal mesothelial cells. Journal of cell science124(10), 1644-1654.

Leca, G., Mansur, S. E., & Bensussan, A. (1995). Expression of VCAM-1 (CD106) by a subset of TCR gamma delta-bearing lymphocyte clones. Involvement of a metalloprotease in the specific hydrolytic release of the soluble isoform. The Journal of Immunology154(3), 1069-1077.


Availability: In stock

Size Price Qty
25 tests
$110.00
100 tests
$240.00
Additional STA Formats
Cat.No. Format Starting From
18111-60PE $ 110.00
18111-80APC $ 140.00
18111-30Biotin $ 180.00