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Animal-Free Recombinant Human VEGF 121



Catalog Number : AF-100-20A

Description

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant human VEGF121 is a 28.4 kDa disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml.
 
AA Sequence
APMAEGGGQ NHHEVVKFM DVYQRSYCH PIETLVDIF QEYPDEIEY IFKPSCVPL MRCGGCCND EGLECVPTE ESNITMQIM RIKPHQGQH IGEMSFLQH NKCECRPKK DRARQENCD KPRR
Research Interest: Stem Cell Research, Cancer, Angiogenesis, Inflammation, Proliferation and Cell Cycle
Cell Type: Monocytes and Macrophages, Stem Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
10µg
$215.00
100µg
$860.00
500µg
$2,580.00
1mg
$4,300.00