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Animal-Free Recombinant Human IL-17E



Catalog Number : AF-200-24

Description

IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng.
 
AA Sequence
MYSHWPSCC PSKGQDTSE ELLRWSTVP VPPLEPARP NRHPESCRA SEDGPLNSR AISPWRYEL DRDLNRLPQ DLYHARCLC PHCVSLQTG SHMDPRGNS ELLYHNQTV FYRRPCHGE KGTHKGYCL ERRLYRVSL ACVCVRPRV MG
Research Interest: Inflammation
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
25µg
$215.00
100µg
$660.00
500µg
$1,980.00
1mg
$3,300.00