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Animal-Free Recombinant Human IL-16 (121 a.a.)



Catalog Number : AF-200-16A

Description

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability ot chemoattract human CD4+ T-Lymphocytes using a concentration range of 50.0-100.0 ng/ml.
 
AA Sequence
SAASASAAS DVSVESTAE ATVCTVTLE KMSAGLGFS LEGGKGSLH GDKPLTINR IFKGAASEQ SETVQPGDE ILQLGGTAM QGLTRFEAW NIIKALPDG PVTIVIRRK SLQSKETTA AGDS
Research Interest: Adaptive Immunity, Apoptosis
Cell Type: Monocytes and Macrophages, T Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
10µg
$215.00
100µg
$1,140.00
500µg
$3,420.00
1mg
$5,700.00