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Animal-Free Recombinant Human IL-15



Catalog Number : AF-200-15

Description

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 12.9 kDa protein consisting of 114 amino acid residues. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Monkey, Mouse
 
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells was found to be ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
 
AA Sequence
MNWVNVISD LKKIEDLIQ SMHIDATLY TESDVHPSC KVTAMKCFL LELQVISLE SGDASIHDT VENLIILAN NSLSSNGNV TESGCKECE ELEEKNIKE FLQSFVHIV QMFINTS
Research Interest: Innate Immunity, Adaptive Immunity, Stem Cell Research, Apoptosis, Immunology, Cancer, Inflammation
Cell Type: NK and NKT Cells, T Cells
Protein Cross Reactivity: Monkey, Mouse

Availability: In stock

Size Price Qty
10µg
$215.00
100µg
$860.00
500µg
$2,580.00
1mg
$4,300.00