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Animal-Free Recombinant Human IL-11



Catalog Number : AF-200-11

Description

IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.3 kDa protein consisting of 179 amino acid residues. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Monkey, Mouse
 
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
 
AA Sequence
MPGPPPGPP RVSPDPRAE LDSTVLLTR SLLADTRQL AAQLRDKFP ADGDHNLDS LPTLAMSAG ALGALQLPG VLTRLRADL LSYLRHVQW LRRAGGSSL KTLEPELGT LQARLDRLL RRLQLLMSR LALPQPPPD PPAPPLAPP SSAWGGIRA AHAILGGLH LTLDWAVRG LLLLKTRL
Research Interest: Adaptive Immunity, Stem Cell Research, Apoptosis, Immunology, Cancer, Angiogenesis, Inflammation
Cell Type: T Cells, Stem Cells
Protein Cross Reactivity: Monkey, Mouse

Availability: In stock

Size Price Qty
10µg
$215.00
100µg
$1,140.00
500µg
$3,420.00
1mg
$5,700.00