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Animal-Free Recombinant Human FGF-basic (154 a.a.)



Catalog Number : AF-100-18B

Description

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
 
Purity:
Above 95% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken
 
Biological Activity
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 u
 
AA Sequence
AAGSITTLP ALPEDGGSG AFPPGHFKD PKRLYCKNG GFFLRIHPD GRVDGVREK SDPHIKLQL QAEERGVVS IKGVCANRY LAMKEDGRL LASKCVTDE CFFFERLES NNYNTYRSR KYTSWYVAL KRTGQYKLG SKTGPGQKA ILFLPMSAK S
Research Interest: Stem Cell Research, Cancer, Angiogenesis, Neurosciences, Inflammation, Proliferation and Cell Cycle
Cell Type: Monocytes and Macrophages, Stem Cells, Endothelial Cells, Neurons
Protein Cross Reactivity: Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken

Availability: In stock

Size Price Qty
50µg
$215.00
100µg
$235.00
500µg
$510.00
1mg
$850.00