ALK5 Inhibitor (RepSox) hydrochloride

Grouped product items
SizePrice Qty
10mg
$110.00
25mg
$235.00
Catalog Number : 2310749

description

The ALK5 inhibitor selectively inhibits TGF-Beta receptor signaling, useful for enhancing the efficiency of cellular reprogramming. It is also reported to induce the differentiation of pancreatic progenitor cells into insulin-producing cells. 

 
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Additional Information

Applications:
FA
Synonyms:
RepSox, ALK5 Inhibitor II, E616452
Formulation:
Crystalline solid
Chemical Name:

2-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine, monohydrochloride

Molecular Formula:

C17H13N5

HCl
Molecular Weight:
323.8
CAS Number
2319939-07-4
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Woltjen, K., & Stanford, W. L. (2009). Inhibition of Tgf-β Signaling Improves Mouse Fibroblast Reprogramming. Cell stem cell5(5), 457-458.

Larsen, D. M. (2013). Evaluation of the TGF-beta inhibitor RepSox on the expression of pluripotency pathways in murine and bovine cells. UTAH STATE UNIVERSITY.

Jajosky, A. N., Coad, J. E., Vos, J. A., Martin, K. H., Senft, J. R., Wenger, S. L., & Gibson, L. F. (2014). RepSox Slows Decay of CD34+ Acute Myeloid Leukemia Cells and Decreases T Cell Immunoglobulin Mucin-3 Expression.Stem cells translational medicine3(7), 836.

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