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1-EBIO



Catalog Number : 1004515

Description

1-EBIO is an epithelial Ca2+-activated K+ and CFTR channel activator. It is reported to enhance the differentiation of embryonic stem cells into cardiomyocytes.
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Additional Information

Applications
FA
Synonyms:
1-ethyl-2-benzimidazolinone, 1-Ethylbenzimidazolinone, 1-EB10
Formulation:
Crystalline solid
Chemical Name:
3-ethyl-1H-benzimidazol-2-one
Molecular Formula:

C9H10N2O

Molecular Weight:
162.2
CAS Number
10045-45-1
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:
Anderson, N. J., Slough, S., & Watson, W. P. (2006). In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsant. European journal of pharmacology, 546(1-3), 48-53. Walker, S. D., Dora, K. A., Ings, N. T., Crane, G. J., & Garland, C. J. (2001). Activation of endothelial cell IKCa with 1‐ethyl‐2‐benzimidazolinone evokes smooth muscle hyperpolarization in rat isolated mesenteric artery. British journal of pharmacology, 134(7), 1548-1554. Müller, M., Stockmann, M., Malan, D., Wolheim, A., Tischendorf, M., Linta, L., ... & Wobus, A. M. (2012). Ca2+ activated K channels-new tools to induce cardiac commitment from pluripotent stem cells in mice and men. Stem Cell Reviews and Reports, 8(3), 720-740.

Availability: In stock

Size Price Qty
10mg
$45.00
50mg
$175.00