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Anti-Mouse F4/80 Antigen BG Violet 450



Catalog Number : 02922-40

Description

The BM8.1 monoclonal antibody specifically binds to the Mouse125 kDa F4/80 antigen, expressed by most mature macrophages. F4/80 is a transmembrane protein used as a marker of macrophages, although it is also expressed on Kupffer and Langerhans cells. The expression of F4/80 antigen is upregulated on bone marrow cells stimulated in vitro with the macrophage colony stimulating factor. The F4/80 antigen is a requirement for the induction of CD8 T cells-mediated peripheral tolerance.

BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Additional Information

Clone
BM8.1
Format:
BG Violet 450
Applications
FC
Reactivity
Mouse
Isotype:
Rat IgG2a, kappa
Research Interest: Innate Immunity
Cell Type: Monocytes and Macrophages, Dendritic Cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Zwadlo, G., Bröcker, E. B., Von Bassewitz, D. B., Feige, U., & Sorg, C. (1985). A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes. The Journal of Immunology134(3), 1487-1492.

Leenen, P. J., de Bruijn, M. F., Voerman, J. S., Campbell, P. A., & van Ewijk, W. (1994). Markers of mouse macrophage development detected by monoclonal antibodies. Journal of immunological methods174(1), 5-19.

Schaller, E., Macfarlane, A. J., Rupec, R. A., Gordon, S., McKnight, A. J., & Pfeffer, K. (2002). Inactivation of the F4/80 glycoprotein in the mouse germ line.Molecular and cellular biology22(22), 8035-8043.


Availability: In stock

Size Price Qty
25 μg
$155.00
100 μg
$350.00
Additional BM8.1 Formats
Cat.No. Format Starting From
02922-70PerCP-Cyanine5.5 $ 145.00
02922-60PE $ 65.00
02922-50FITC $ 50.00
02922-80APC $ 75.00
02922-40BG Violet 450 $ 155.00
02922-30Biotin $ 45.00
02922-20Purified $ 135.00