Anti-Mouse IL-4 SAFIRE Purified

Grouped product items
Size Price Qty
100 μg
$185.00
500 μg
$225.00

Additional 11B11 Formats

Cat.No. Format Starting From
81112-60 PE $ 70.00
81112-20 Purified $ 105.00
81112-25 SAFIRE Purified $ 185.00
81112-80 APC $ 70.00
Catalog Number : 81112-25

description

The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.

The 11B11 antibody neutralizes the IL-4 cytokine.

Additional Information

Clone:
11B11
Format:
SAFIRE Purified
Applications:
FC, FA, IHC, IF, ELISA
Reactivity:
Mouse
Isotype:
Rat IgG1, kappa
Research Interest: Innate Immunity
Cell Type: T Cells
Application: FC, FA, IHC, IF, ELISA
Clone: 11B11
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Abrams, John S. Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. John Wiley & Sons, Inc., 1995.

Ohara, J., and W. E. Paul. "Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1." Nature 315.6017 (1985): 333.

Haak-Frendscho, M., Brown, J. F., Iizawa, Y. U. J. I., Wagner, R. D., & Czuprynski, C. J. (1992). Administration of anti-IL-4 monoclonal antibody 11B11 increases the resistance of mice to Listeria monocytogenes infection. The Journal of Immunology148(12), 3978-3985.

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