Anti-Mouse CD45.1 Purified
Additional A20 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 07522-60 | PE | $ 65.00 |
| 07522-70 | PerCP-Cyanine5.5 | $ 90.00 |
| 07522-77 | PE-Cyanine7 | $ 55.00 |
| 07522-40 | BG Violet 450 | $ 85.00 |
| 07522-20 | Purified | $ 80.00 |
| 07522-50 | FITC | $ 45.00 |
| 07522-87 | APC-Cyanine7 | $ 90.00 |
| 07522-80 | APC | $ 70.00 |
description
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors. The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
Additional Information
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Clone:
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A20
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Format:
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Purified
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Applications:
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FC, IHC, IP
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Reactivity:
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Mouse
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Isotype:
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Mouse IgG2a, kappa
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | B Cells, Macrophage / Monocyte, NK and NKT Cells, T Cells |
| Application: | FC, IHC, IP |
| Clone: | A20 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Shen, F.W. (1981) Monoclonal antibodies to mouse lymphocyte differentiation alloantigens. Monoclonal Antibodies and T-Cell Hybridomas: Perspectives and Technical Advances. G.J. Hämmerling, U. Hämmerling, and J.F. Kearney, editors. Elsevier/North-Holland, Amsterdam. pp. 25–31. Yakura, H. I. D. E. T. A. K. A., Kawabata, I., Shen, F. W., & Katagiri, M. (1986). Selective inhibition of lipopolysaccharide-induced polyclonal IgG response by monoclonal Ly-5 antibody. The Journal of Immunology, 136(8), 2729-2733. Yakura, H., Shen, F. W., Bourcet, E., & Boyse, E. A. (1983). On the function of Ly-5 in the regulation of antigen-driven B cell differentiation. Comparison and contrast with Lyb-2. The Journal of experimental medicine, 157(4), 1077-1088. |