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Anti-Mouse CD127 (IL-7Ra) BG Violet 450



Catalog Number : 19212-40

Description

The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.

The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.

BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Additional Information

Clone
A7R34
Format:
BG Violet 450
Applications
FC
Reactivity
Mouse
Isotype:
Rat IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells, T Cells, Treg cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Sudo, T., Nishikawa, S. A. T. O. M. I., Ohno, N. O. R. I. K. O., Akiyama, N. A. O. K. O., Tamakoshi, M. A. S. A. T. A. D. A., & Yoshida, H. I. S. A. H. I. R. O. (1993). Expression and function of the interleukin 7 receptor in murine lymphocytes. Proceedings of the National Academy of Sciences90(19), 9125-9129.

Hashi, H., Yoshida, H., Honda, K., Fraser, S., Kubo, H., Awane, M., ... & Nishikawa, S. I. (2001). Compartmentalization of Peyer’s patch anlagen before lymphocyte entry. The Journal of Immunology166(6), 3702-3709.

Okuno, Y., Iwasaki, H., Huettner, C. S., Radomska, H. S., Gonzalez, D. A., Tenen, D. G., & Akashi, K. (2002). Differential regulation of the human and murine CD34 genes in hematopoietic stem cells. Proceedings of the National Academy of Sciences99(9), 6246-6251.


Availability: In stock

Size Price Qty
25 μg
$135.00
100 μg
$315.00
Additional A7R34 Formats
Cat.No. Format Starting From
19212-60PE $ 60.00
19212-70PerCP-Cyanine5.5 $ 75.00
19212-77PE-Cyanine7 $ 95.00
19212-40BG Violet 450 $ 135.00
19212-20Purified $ 135.00
19212-50FITC $ 40.00
19212-30Biotin $ 45.00
19212-80APC $ 80.00