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Anti-Mouse CD117 (c-Kit) SAFIRE Purified



Catalog Number : 19112-25

Description

The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.

Additional Information

Clone
ACK2
Format:
SAFIRE Purified
Applications
FC, FA, IHC, ICC, WB
Reactivity
Mouse
Isotype:
Rat IgG2b, kappa
Preperation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., & Zlotnik, A. (1994). Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation. The Journal of Immunology152(10), 4783-4792.

Godfrey, D. I., Zlotnik, A. L. B. E. R. T., & Suda, T. A. K. A. S. H. I. (1992). Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. The Journal of Immunology149(7), 2281-2285.

Feng, H., Sandlow, J. I., & Sandra, A. (1998). The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa. Molecular reproduction and development49(3), 317-326.


Availability: In stock

Size Price Qty
100 μg
$135.00
500 μg
$250.00
Additional ACK2 Formats
Cat.No. Format Starting From
19112-60PE $ 50.00
19112-20Purified $ 115.00
19112-25SAFIRE Purified $ 135.00
19112-80APC $ 70.00
19112-77PE-Cyanine7 $ 65.00