Anti-Human CD79a PerCP-Cyanine5.5
Additional HM47 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 09511-70 | PerCP-Cyanine5.5 | $ 615.00 |
| 09511-60 | PE | $ 240.00 |
Catalog Number : 09511-70
description
The HM47 monoclonal antibody reacts with the cytoplasmic domain of CD79a, a 47kDa type I integral membrane protein known as Iga or mb-1. It forms the part of the B-cell receptor complex with CD79b and is expressed on B cells from earliest pre-B to plasma cell stage. It is also reported that CD79a expresses weakly on myeloid cells and T cell precursors. CD79a is believed to be involved in transporting IgM to the surface of B cells.
Additional Information
|
Clone:
|
HM47
|
|
Format:
|
PerCP-Cyanine5.5
|
|
Applications:
|
FC
|
|
Reactivity:
|
Human, Mouse
|
|
Isotype:
|
Mouse IgG1, kappa
|
| Research Interest: | Adaptive Immunity |
|---|---|
| Cell Type: | B Cells |
| Application: | FC |
| Clone: | HM47 |
|
Preparation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
|
References:
|
Mason, D. Y., Cordell, J. L., Tse, A. G., Van Dongen, J. J., Van Noesel, C. J., Micklem, K., ... & Borst, J. (1991). The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells. Journal of immunology (Baltimore, Md.: 1950), 147(11), 2474-2482. Bhargava, P., Kallakury, B. V., Ross, J. S., Azumi, N., & Bagg, A. (2007). CD79a is heterogeneously expressed in neoplastic and normal myeloid precursors and megakaryocytes in an antibody clone–dependent manner.American journal of clinical pathology, 128(2), 306-313. Hashimoto, M., Yamashita, Y., & Mori, N. (2002). Immunohistochemical detection of CD79a expression in precursor T cell lymphoblastic lymphoma/leukaemias. The Journal of pathology, 197(3), 341-347. |