Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Anti-Human CD54 (ICAM-1) PE



Catalog Number : 06611-60

Description

The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).

The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.

Additional Information

Clone
15.2
Format:
PE
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1
Research Interest: Adaptive Immunity, Angiogenesis
Cell Type: B Cells, Monocytes and Macrophages, T Cells, Dendritic Cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Bhattacharya, A. L. O. K., Dorf, M. E., & Springer, T. A. (1981). A shared alloantigenic determinant on Ia antigens encoded by the IA and IE subregions: evidence for I region gene duplication. The Journal of Immunology127(6), 2488-2495.

Mendiratta, S. K., Singh, N., Bal, V., & Rath, S. (1996). Analysis of T-cell hybridomas with an unusual MHC class II-dependent ligand specificity.Immunology89(2), 238-244.

Unternaehrer, J. J., Chow, A., Pypaert, M., Inaba, K., & Mellman, I. (2007). The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proceedings of the National Academy of Sciences,104(1), 234-239.


Availability: In stock

Size Price Qty
25 tests
$95.00
100 tests
$240.00
Additional 15.2 Formats
Cat.No. Format Starting From
06611-60PE $ 95.00
06611-20Purified $ 105.00
06611-25SAFIRE Purified $ 195.00
06611-50FITC $ 85.00
06611-80APC $ 120.00