Anti-Human CD45RO Biotin

Grouped product items
Size Price Qty
100 ug
$145.00

Additional UCHL1 Formats

Cat.No. Format Starting From
07141-60 PE $ 80.00
07141-20 Purified $ 75.00
07141-50 FITC $ 70.00
07141-80 APC $ 100.00
07141-70 PerCP-Cyanine5.5 $ 135.00
07141-30 Biotin $ 145.00
Catalog Number : 07141-30

description

The UCHL1 monoclonal antibody specifically reacts with human CD45RO, a 180 kDa isoform of the leukocyte common antigen CD45. CD45RO is a transmembrane glycoprotein with tyrosine phosphatase activity and is expressed by majority of thymocytes, monocytes, granulocytes, and activated memory T lymphocytes. The subsets of peripheral T lymphocytes can be discriminated by using the CD45RO and CD45RA expressing cells.

Additional Information

Clone:
UCHL1
Format:
Biotin
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: Macrophage / Monocyte, B Cells, T Cells
Application: FC
Clone: UCHL1
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Akbar, A. N., Terry, L., Timms, A., Beverley, P. C., & Janossy, G. (1988). Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. The Journal of Immunology140(7), 2171-2178.

Smith, S. H., Brown, M. H., Rowe, D., Callard, R. E., & Beverley, P. C. (1986). Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1. Immunology58(1), 63.

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