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Anti-Human CD4 PE-Cyanine7



Catalog Number : 06121-77

Description

The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II.

The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.

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Human peripheral blood lymphocytes were stained with PE-Cy7 RPA-T4 with relevant isotype control in Red.
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Additional Information

Clone
RPA-T4
Format:
PE-Cyanine7
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: Monocytes and Macrophages, T Cells, Treg cells, Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York


Availability: In stock

Size Price Qty
25 tests
$115.00
100 tests
$240.00
Additional RPA-T4 Formats
Cat.No. Format Starting From
06121-20Purified $ 65.00
06121-60PE $ 50.00
06121-77PE-Cyanine7 $ 115.00
06121-40BG Violet 450 $ 85.00
06121-50FITC $ 40.00
06121-87APC-Cyanine7 $ 115.00
06121-80APC $ 70.00
06121-70PerCP-Cyanine5.5 $ 90.00