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Anti-Human CD3 FITC



Catalog Number : 05121-50

Description

The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

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Human peripheral blood lymphocytes were stained with FITC OKT3 with relevant isotype control in Red.
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Additional Information

Clone
OKT3
Format:
FITC
Applications
FC
Reactivity
Human
Isotype:
MouseIgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells, Treg cells, Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., ... & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies5(1), 41-47.


Availability: In stock

Size Price Qty
25 tests
$40.00
100 tests
$90.00
Additional OKT3 Formats
Cat.No. Format Starting From
05121-20Purified $ 115.00
05121-25SAFIRE Purified $ 160.00
05121-40BG Violet 450 $ 95.00
05121-60PE $ 50.00
05121-80APC $ 65.00
05121-50FITC $ 40.00
05121-70PerCP-Cyanine5.5 $ 135.00
05121-77PE-Cyanine7 $ 95.00