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Anti-Human CD3 FITC



Catalog Number : 05111-50

Description

The Hit3a monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.

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Human peripheral blood lymphocytes were stained with FITC Hit3a with relevant isotype control in Red.
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Additional Information

Clone
Hit3a
Format:
FITC
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells, Treg cells, Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

McMichael, A. J. (1987). Leucocyte typing III. Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Lanier, L. L., Allison, J. P., & Phillips, J. H. (1986). Correlation of cell surface antigen expression on human thymocytes by multi-color flow cytometric analysis: implications for differentiation. The Journal of Immunology137(8), 2501-2507.


Availability: In stock

Size Price Qty
25 tests
$40.00
100 tests
$85.00
Additional Hit3a Formats
Cat.No. Format Starting From
05111-50FITC $ 40.00
05111-60PE $ 50.00
05111-20Purified $ 80.00
05111-80APC $ 65.00