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Anti-Human CD11b FITC



Catalog Number : 03211-50

Description

The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.

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Human peripheral blood monocytes were stained with FITC ICRF44 with relevant isotype control in Red.
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Additional Information

Clone
ICRF44
Format:
FITC
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity, Angiogenesis
Cell Type: Monocytes and Macrophages, NK and NKT Cells
Protein Cross Reactivity: Baboon, Chimpanzee, Cynomolgus, Rhesus, Swine
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., & van der Merwe, P. A. (1997). The leucocyte antigen factsbook. Academic Press.

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Sotiriou, S. N., Orlova, V. V., Al-Fakhri, N., Ihanus, E., Economopoulou, M., Isermann, B., ... & Chavakis, T. (2006). Lipoprotein (a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin. The FASEB journal20(3), 559-561.


Availability: In stock

Size Price Qty
25 tests
$75.00
100 tests
$165.00
Additional ICRF44 Formats
Cat.No. Format Starting From
03211-60PE $ 80.00
03211-77PE-Cyanine7 $ 115.00
03211-20Purified $ 85.00
03211-50FITC $ 75.00
03211-80APC $ 80.00