Anti-Human CD105 (Endoglin) PE

Grouped product items
Size Price Qty
25 tests
$175.00
100 tests
$400.00

Additional SN6 Formats

Cat.No. Format Starting From
17111-60 PE $ 175.00
17111-80 APC $ 250.00
Catalog Number : 17111-60

description

The SN6 monoclonal antibody specifically reacts with human CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells, activated macrophages, and a subset of bone marrow cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
product image
Viable U937 cells were stained with PE SN6 in purple with relevant isotype control in blue.

Additional Information

Clone:
SN6
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1
Research Interest: Stem Cell Research, Angiogenesis
Cell Type: Macrophage / Monocyte, Stem Cells
Application: FC
Clone: SN6
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., & Leone, G. (2001). CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia & lymphoma42(6), 1195-1206.

She, X., Matsuno, F., Harada, N., Tsai, H., & Seon, B. K. (2004). Synergy between anti‐endoglin (CD105) monoclonal antibodies and TGF‐β in suppression of growth of human endothelial cells. International journal of cancer108(2), 251-257.

Seon, B. K., & Kumar, S. (2002). CD105 antibody for targeting of tumor vascular endothelial cells. In The new angiotherapy (pp. 499-515). Humana Press.

© BioGems International, Inc. All rights reserved.