TTNPB
description
Additional Information
Applications:
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FA
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Synonyms:
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AGN-191183, Arotinoid acid, Arotinoic acid, Ro 13-7410
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Formulation:
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Crystalline solid
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Chemical Name:
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4-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid
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Molecular Formula:
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C24H28O2 |
Molecular Weight: |
348.5
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CAS Number
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71441-28-6
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Pignatello, M. A., Kauffman, F. C., & Levin, A. A. (1997). Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicology and applied pharmacology, 142(2), 319-327. Åström, A., Pettersson, U., Krust, A., Chambon, P., & Voorhees, J. J. (1990). Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription. Biochemical and biophysical research communications, 173(1), 339-345. Hossain, M. Z., & Bertram, J. S. (1994). Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells: implications for the role of gap junctional communication. Cell growth & differentiation: the molecular biology journal of the American Association for Cancer Research, 5(11), 1253-1261. |