TTNPB

Grouped product items
Size Price Qty
1mg
$45.00
10mg
$175.00
Catalog Number : 7142861

description

TTNPB is a retinoic acid analog that selectively and potently activates the retinoic acid receptors. It is reported to increase the efficiency of induced pluripotent stem cell (iPSC) chemical reprogramming.

Additional Information

Applications:
FA
Synonyms:
AGN-191183, Arotinoid acid, Arotinoic acid, Ro 13-7410
Formulation:
Crystalline solid
Chemical Name:
4-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid
Molecular Formula:

C24H28O2

Molecular Weight:
348.5
CAS Number
71441-28-6
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Pignatello, M. A., Kauffman, F. C., & Levin, A. A. (1997). Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicology and applied pharmacology142(2), 319-327.

Åström, A., Pettersson, U., Krust, A., Chambon, P., & Voorhees, J. J. (1990). Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription. Biochemical and biophysical research communications173(1), 339-345.

Hossain, M. Z., & Bertram, J. S. (1994). Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells: implications for the role of gap junctional communication. Cell growth & differentiation: the molecular biology journal of the American Association for Cancer Research5(11), 1253-1261.

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